Senescence-associated β-galactosidase activity in the developing avian retina.
José Antonio de Mera-RodríguezGuadalupe Álvarez-HernánYolanda GañánGervasio Martín-PartidoJoaquín Rodríguez-LeónJavier Francisco MorcilloPublished in: Developmental dynamics : an official publication of the American Association of Anatomists (2019)
In conclusion, the results clearly show that SA-β-GAL activity cannot be regarded as a specific marker of senescence during retinal development, and that it is mainly expressed in subpopulations of postmitotic neurons, which are nonproliferative cells, even at early stages of cell differentiation.