Pharmacogenetics of artemether-lumefantrine influence on nevirapine disposition: Clinically significant drug-drug interaction?

Sa'ad T AbdullahiAdeniyi OlagunjuJulius O SoyinkaRahman A BolarinwaOlusola J OlarewajuMoji T Bakare-OdunolaAndrew OwenSaye Khoo

Published in: British journal of clinical pharmacology (2019)

This approach highlights additional increase in the already existing risk of suboptimal trough plasma concentration, especially in extensive metabolizers when nevirapine is co-administered with artemether-lumefantrine.

Keyphrases

drug induced
emergency department