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RANCM: a new ranking scheme for assigning confidence levels to metabolite assignments in NMR-based metabolomics studies.

William C JoestenMichael A Kennedy
Published in: Metabolomics : Official journal of the Metabolomic Society (2019)
RANCM is intended to reduce the ambiguity in "putatively annotated compound" assignments, to facilitate effective communication of the degree of confidence in "putatively annotated compound" assignments, and to make it easier for non-experts to evaluate the significance and reliability of NMR-based metabonomics studies. The system is straightforward to implement, based on the most common datasets collected in NMR-based metabolic profiling studies, and can be used with equal rigor and significance with any set of NMR datasets.
Keyphrases
  • magnetic resonance
  • high resolution
  • solid state
  • case control
  • mass spectrometry