Aged versus fresh autologous platelet transfusion in a two-hit healthy volunteer model of transfusion-related acute lung injury.
Frank E H P van BaarleSanne de BruinEsther B BulleNiels van MourikEndry H T LimAnita M Tuip-de BoerAnnabel BongersMarit B de WisselRobin van BruggenDirk de KorteChristie VermeulenKhik Wie TanRené E JonkersPeter I BontaRené LutterTamara DekkerBarbara S DierdorpAnna L PetersBart J BiemondAlexander P J VlaarPublished in: Transfusion (2022)
In a human endotoxemia model of autologous platelet transfusion, with an adequate first hit and platelet storage lesion, transfusion of 7-day-old PC does not increase pulmonary inflammation compared with 2-day-old PC.