β-Catenin in the kidney stroma modulates pathways and genes to regulate kidney development.
Erin DeaconAnna LiFelix BoivinAnna Dvorkin-GhevaJoanna CunananDarren BridgewaterPublished in: Developmental dynamics : an official publication of the American Association of Anatomists (2023)
These studies advance our understanding of gene and biological pathway dysregulation in the context of stromal β-catenin misexpression during kidney development. Our findings suggest that during normal kidney development, stromal β-catenin may regulate secreted and cell-surface proteins to communicate with adjacent cell populations.