Serpin B9 controls tumor cell killing by CAR T cells.

Thomas KimmanAnne SlompAnne MartensSarah GrabherrShuang LiEline van DiestJan MeeldijkJürgen H E KuballMonique C MinnemaEric ElderingNiels BovenschenZsolt SebestyénVictor Peperzak

Published in: Journal for immunotherapy of cancer (2023)

Overall, the data indicate that serpin B9 is a resistance mediator for CAR T cell-mediated tumor cell killing that should be inhibited or bypassed to improve CAR T-cell responses.

Keyphrases

single cell
cell therapy
stem cells
electronic health record
big data
artificial intelligence