HSF1 is involved in suppressing A1 phenotype conversion of astrocytes following spinal cord injury in rats.

Lilan LiYu LiBingqiang HeHui LiHuiyuan JiYingjie WangZhenjie ZhuYuming HuYue ZhouTing YangChunshuai SunYing YuanYongjun Wang

Published in: Journal of neuroinflammation (2021)

Collectively, these data reveal a novel mechanism of astrocyte phenotype conversion following SCI, and HSF1 plays key roles in suppressing excessive increase of neurotoxic A1 astrocytes.

Keyphrases

spinal cord
heat shock
spinal cord injury
signaling pathway
electronic health record
neuropathic pain
genome wide
weight gain
big data
single cell
gene expression
body mass index
deep learning