A call for discovery: Re-envisioning The Cancer Genome Atlas as a blueprint for a TCGA2.0-The COVID-19 Genome Atlas.
Kristian M HargadonPublished in: Clinical and translational discovery (2021)
The COVID-19 pandemic has impacted the health of millions and had a myriad of devastating consequences for global societies since its emergence in 2019. Noting parallels between the impact of COVID-19 and cancer as diseases of global health significance, and as a way of building off the successes of The Cancer Genome Atlas (TCGA) as a comprehensive, multiomics approach to understand and combat cancer, this Call For Discovery provides a vision for creating a new TCGA2.0 (The COVID-19 Genome Atlas) as a tool that will benefit researchers, clinicians, and patients alike as the scientific community works to better understand not only the various determinants of COVID-19 disease outcome but also the most effective ways to manage and treat COVID-19 disease complications.
Keyphrases
- coronavirus disease
- sars cov
- papillary thyroid
- squamous cell
- healthcare
- single cell
- public health
- small molecule
- genome wide
- respiratory syndrome coronavirus
- mental health
- newly diagnosed
- gene expression
- squamous cell carcinoma
- ejection fraction
- dna methylation
- risk assessment
- young adults
- patient reported outcomes
- health promotion
- patient reported