Multivariate Analyses Reveal Biological Components Related to Neuronal Signaling and Immunity Mediating Electroencephalograms Abnormalities in Alcohol-Dependent Individuals from the Collaborative Study on the Genetics of Alcoholism Cohort.

Shashwath A MedaBalaji NarayananDavid ChorlianJacquelyn L MeyersJoel GelernterVictor M HesselbrockLance BauerVince D CalhounBernice PorjeszGodfrey D Pearlson

Published in: Alcoholism, clinical and experimental research (2019)

Our data suggest plausible multifactorial genetic components, primarily enriched for neuronal/synaptic signaling/transmission, immunity, and neurogenesis, mediating low-frequency alpha and theta abnormalities in alcohol addiction.

Keyphrases

cerebral ischemia
genome wide
alcohol consumption
data analysis
electronic health record
big data
dna methylation
quality improvement
brain injury
high frequency
neural stem cells