Allele-Specific MicroRNA-Mediated Regulation of a Glycolysis Gatekeeper PDK1 in Cancer Metabolism.

Sugarniya SubramaniamVarinder Jeet Jennifer H GunterJudith A ClementsJyotsna Batra

Published in: Cancers (2021)

The present study is the first to report the regulation of the PDK1 gene by miRNAs in an allele-dependent manner and highlights the role of PDK1 in metabolic adaption associated with PCa progression.

Keyphrases

papillary thyroid
genome wide
squamous cell
copy number
transcription factor
young adults