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Moxifloxacin Concentrations in the Knee Joint, Tibial Bone, and Soft Tissue When Combined with Rifampicin: A Randomized Porcine Microdialysis Study.

Josefine SlaterMaiken StillingPelle HanbergMathias Alrø Fichtner BendtsenAndrea René JørgensenKjeld SøballeNis Pedersen JørgensenMats Bue
Published in: The Journal of bone and joint surgery. American volume (2021)
The concentrations within the targeted tissue compartments were reduced significantly more than the concentrations in plasma, which may be particularly important as plasma concentrations are used in clinical practice to assess moxifloxacin treatment sufficiency.
Keyphrases
  • soft tissue
  • clinical practice
  • total knee arthroplasty
  • mycobacterium tuberculosis