Modulation of Innate Immunity by G-CSF and Inflammatory Response by LBPK95A Improves the Outcome of Sepsis in a Rat Model.

Haoshu FangChuanfeng HuaStefanie WeissAnding LiuWenhui ChengRalf ClausJürgen RödelOlaf DirschUta Dahmen

Published in: Journal of immunology research (2018)

Our results revealed that increasing innate immunity by G-CSF pretreatment and decreasing inflammatory responses using LBPK95A improved the survival rates in a rat sepsis model and could be a novel strategy to treat sepsis.

Keyphrases

septic shock
acute kidney injury
inflammatory response
intensive care unit
lipopolysaccharide induced