Scrub Typhus Masquerading as Limbic Encephalitis.
Subhrajyoti BiswasRitwik GhoshDipayan RoyAdrija RayKaustav DeSubrata BiswasDinabandhu NagaJulián Benito-LeónPublished in: The Neurohospitalist (2021)
Scrub typhus, an acute febrile infectious disease prevalent in the 'tsutsugamushi triangle', is a mite-born rickettsial zoonosis, caused by Orientia tsutsugamushi. The clinical presentation is protean and involves multiple organ systems of the body, including central and peripheral nervous systems. We report a 22-year-old previously healthy Indian woman who presented with clinical (confusion, excessive sleepiness, cognitive dysfunction and focal seizures) and neuroimaging features of limbic encephalitis. After exclusion of common infectious, autoimmune and paraneoplastic causes, she was diagnosed with scrub typhus associated encephalitis, which responded to doxycycline and azithromycin therapy.
Keyphrases
- infectious diseases
- liver failure
- drug induced
- obstructive sleep apnea
- multiple sclerosis
- chemotherapy induced
- sleep quality
- stem cells
- respiratory failure
- sleep apnea
- low birth weight
- depressive symptoms
- urinary tract infection
- intensive care unit
- physical activity
- bone marrow
- extracorporeal membrane oxygenation
- preterm birth
- smoking cessation