Adverse events of metronidazole and amoxicillin: Retrospective analysis of a large data set of five randomized clinical trials.

Belen Retamal-ValdesAna Paula Laranjeira TavaresSarah MoniqueHélio Doyle Pereira da SilvaMaria Josefa MestnikPoliana Mendes Duarte Tamires Szeremeske de MirandaIvan BorgesGeisla Mary Silva SoaresMarcelo FaveriNidia Castro Dos SantosYasmin Teixeira das GraçasMaria Luisa Silveira SoutoMarcela GiudicissiGiuseppe Alexandre Romito Luciana SaraivaClaudio Mendes PannutiLuciene Cristina de FigueiredoMagda Feres

Published in: Journal of clinical periodontology (2022)

The occurrence of side effects during MTZ + AMX treatment ranged from uncommon (1%) to very common (17.7%). The main factors raising the chances of a patient reporting adverse events were diabetes and taking antibiotics in the healing phase, instead of in the active phase of treatment. Patients ≤ 49 years old and females also tend to report more side effects.

Keyphrases

end stage renal disease
type diabetes
ejection fraction
newly diagnosed
clinical trial
prognostic factors
metabolic syndrome
electronic health record
combination therapy
adipose tissue
peritoneal dialysis
machine learning
big data
deep learning
glycemic control
artificial intelligence