In vitro mRNA-S maternal vaccination induced altered immune regulation at the maternal-fetal interface.

Ananth Kumar KammalaMadhuri TatiparthyTilu Jain ThomasSrinivasa Reddy BonamIstvan BoldoghHu HaitaoSurendra SharmaRamkumar Menon

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2024)

In conclusion, our study indicates that mRNA-S-based maternal vaccination during pregnancy may influence the maternal-fetal interface's COVID-19 interaction and immune regulation. Further investigation is warranted to assess safety and implications.

Keyphrases

birth weight
pregnancy outcomes
sars cov
weight gain
pregnant women
gestational age
high glucose
oxidative stress
binding protein
diabetic rats
drug induced
preterm birth
respiratory syndrome coronavirus