hace1 Influences zebrafish cardiac development via ROS-dependent mechanisms.

Babak RazaghiShelby L SteeleSergey V PrykhozhijMatthew R StoyekJessica A HillMatthew D CooperLindsay McDonaldWilliam LinMads DaugaardNicolas CrapouletSimi ChackoStephen M LewisIan C ScottPoul H B SorensenJason N Berman

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2017)

Our study demonstrates that HACE1 is critical in the normal development and proper function of the vertebrate heart via a ROS-dependent mechanism. Developmental Dynamics 247:289-303, 2018. © 2017 Wiley Periodicals, Inc.

Keyphrases

cell death
dna damage
reactive oxygen species
heart failure
left ventricular
atrial fibrillation