Antioxidant effects of LEDT in dystrophic muscle cells: involvement of PGC-1α and UCP-3 pathways.

Guilherme Luiz da RochaDimitrius Santiago Passos Simões Fróes GuimarãesMarcos Vinicius da CruzDaniela Sayuri MizobutiHeloina Nathalliê Mariano da SilvaElaine Cristina Leite PereiraLeonardo Reis SilveiraElaine Minatel

Published in: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology (2023)

The data shown here highlight the potential of LEDT as a therapeutic agent for DMD through its antioxidant action by modulating PGC-1α and UCP3 levels.

Keyphrases

skeletal muscle
induced apoptosis
oxidative stress
anti inflammatory
cell cycle arrest
signaling pathway
duchenne muscular dystrophy
electronic health record
big data
endoplasmic reticulum stress
machine learning
risk assessment