Prognostic Implications of ALDH1 and Notch1 in Different Subtypes of Oral Cancer.
Silas Antonio Juvencio de Freitas FilhoCláudia Malheiros Coutinho CamilloKatia Klug OliveiraBárbara Beltrame BettimClovis Antonio Lopes PintoLuiz Paulo KowalskiDenise Tostes OliveiraPublished in: Journal of oncology (2021)
The strong immunoexpression of Notch1 can contribute to identification of patients with poorly differentiated oral squamous cell carcinoma, who have perineural infiltration or lymph node metastasis. In addition, the strong immunoexpression of ALDH1 may help to identify a worse prognosis in patients with oral squamous cell carcinoma and their subtypes.