Low sun exposure acts synergistically with high Epstein-Barr nuclear antigen 1 (EBNA-1) antibody levels in multiple sclerosis etiology.
Anna Karin HedströmJesse HuangNicole BrennerJulia ButtIngrid KockumTim WaterboerTomas OlssonLars AlfredssonPublished in: European journal of neurology (2021)
Low sun exposure may either directly, or indirectly by affecting vitamin D levels, synergistically reinforce pathogenic mechanisms, such as aspects of the adaptive immune response, related to MS risk conveyed by EBV infection.