Consensus subtypes of hepatocellular carcinoma associated with clinical outcomes and genomic phenotypes.

Sung Hwan LeeSun Young YimYun Seong JeongQi-Xiang LiSang-Hee KangBo Hwa SohnShwetha V KumarJi-Hyun ShinYou Rhee ChoiJae-Jun ShimHayeon KimJi Hoon KimShin KimSheng GuoRandy L JohnsonAhmed KasebKoo Jeong KangYun Shin ChunHee Jin JangByoung Gill LeeHyun Goo WooMin Jin HaRehan AkbaniLewis R RobertsDavid A WheelerJu-Seog Lee

Published in: Hepatology (Baltimore, Md.) (2022)

Five HCC subtypes are correlated with genomic phenotypes and clinical outcomes and highly conserved in preclinical models, providing a framework for selecting the most appropriate models for preclinical studies.

Keyphrases

copy number
cell therapy
transcription factor
clinical practice
gene expression
mesenchymal stem cells
bone marrow