A NIR light-triggered drug delivery system using core-shell gold nanostars-mesoporous silica nanoparticles based on multiphoton absorption photo-dissociation of 2-nitrobenzyl PEG.

Andy Hernández-MontotoMónica GorbeAntoni Llopis-LorenteJosé Manuel TerrésRoberto MontesRoberto Cao-MilánBorja Díaz de GreñuMaría AlfonsoMar OrzaezMaría Dolores MarcosRamón Martínez-MáñezFélix Sancenón

Published in: Chemical communications (Cambridge, England) (2019)

Gold nanostars coated with a mesoporous silica shell and functionalized with poly(ethylene glycol) containing photolabile 2-nitrobenzyl moieties are able to release doxorubicin after NIR light irradiation at low power irradiance via a multiphoton absorption photo-dissociation process.

Keyphrases

electron transfer
drug delivery
photodynamic therapy
drug release
fluorescence imaging
fluorescent probe
silver nanoparticles
cancer therapy
quantum dots
radiation therapy
radiation induced
high resolution