Application of P(VDF-TrFE) Glass Coating for Robust Harmonic Nanoparticles Characterization.

Polyvinylidene fluoride and its copolymers are a well-known family of low-cost ferroelectric materials widely used for the fabrication of devices for a wide range of applications. A biocompatibility, high optical quality, chemical and mechanical durability of poly(vinylidene fluoride-trifluoroethylene), (P(VDF-TrFE)), makes it particularly attractive for designing of effective coating layers for different diagnostic techniques. In the present work, the nonlinear optical characterization of P(VDF-TrFE)-coating films deposited onto a glass substrate was done. Advantages of the coating application for cells/substrates in the field of multiphoton imaging the efficiency of such coating layer for long-duration characterization of so-called harmonic nanoparticles (HNPs) were shown. The influence of glass surface protection by P(VDF-TrFE) film from an effect of HNPs sticking to the walls of the flow-cell was analyzed for effective studying of the optical harmonics generation efficiency of HNPs making the analysis more robust.