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A portable NMR platform with arbitrary phase control and temperature compensation.

Qing YangJianyu ZhaoFrederik DreyerDaniel KrügerJens Anders
Published in: Magnetic resonance (Gottingen, Germany) (2022)
In this paper, we present a custom-designed nuclear magnetic resonance (NMR) platform based on a broadband complementary metal-oxide-semiconductor (CMOS) NMR-on-a-chip transceiver and a synchronous reference signal generator, which features arbitrary phase control of the excitation pulse in combination with phase-coherent detection at a non-zero intermediate frequency (IF). Moreover, the presented direct digital synthesis (DDS)-based frequency generator enables a digital temperature compensation scheme similar to classical field locking without the need for additional hardware. NMR spectroscopy and relaxometry measurements verify the functionality of the proposed frequency reference and temperature compensation scheme as well as the overall state-of-the-art performance of the presented system.
Keyphrases
  • magnetic resonance
  • high resolution
  • high throughput
  • solid state
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  • contrast enhanced
  • computed tomography
  • real time pcr
  • single cell