Different patterns of exosomal α-synuclein between Parkinson's disease and probable rapid eye movement sleep behavior disorder.

Yi-Qun YanJia-Li PuRan ZhengYi FangLu-Yan GuTao GuoXiao-Li SiCheng ZhouYing ChenYi LiuXiao-Jun Guan Xiao-Jun XuYa-Ping YanXin-Zhen YinMin-Ming ZhangZhi-Hua TaoBao-Rong Zhang

Published in: European journal of neurology (2022)

Our results suggest that both t-exo α-Syn and n-exo α-Syn were elevated in the PD group, whilst only n-exo α-Syn was elevated in the pRBD group. Additionally, the adaptor protein of inflammasome ASC is correlated with α-Syn and may facilitate synucleinopathy.

Keyphrases

physical activity
sleep quality
protein protein
small molecule
amino acid
quantum dots