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Molecular Signatures of Mitochondrial Complexes Involved in Alzheimer's Disease via Oxidative Phosphorylation and Retrograde Endocannabinoid Signaling Pathways.

Fenqin ChenJun BaiShanshan ZhongRongwei ZhangXiaoqian ZhangYing XuMei ZhaoChuansheng ZhaoZhike Zhou
Published in: Oxidative medicine and cellular longevity (2022)
Our findings highlight the perturbation of mitochondrial complexes underlying AD onset, which is mediated by molecular signatures involved in oxidative phosphorylation (COX5A, NDUFAB1, SDHB, UQCRC2, and UQCRFS1) and retrograde endocannabinoid signaling (NDUFAB1) pathways.
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