Opioid use disorder in pediatric populations: considerations for perioperative pain management and precision opioid analgesia.
Yun Han ChenAnastasios XenitidisPaul HoffmannLeslie MatthewsSwathi G PadmanabhanLakshmi AravindanRuth ResslerInesh SivamSahana SivamChase F GillispieSenthilkumar SadhasivamPublished in: Expert review of clinical pharmacology (2024)
The opioid and analgesic pharmacogenomics approach can proactively 'tailor' a perioperative analgesic plan to each patient based on underlying polygenic risks. This transition from population-based knowledge of pain medicine to individual patient knowledge can transform acute pain medicine and greatly reduce the opioid epidemic's socioeconomic, personal, and psychological strains globally.
Keyphrases
- pain management
- chronic pain
- healthcare
- cardiac surgery
- case report
- neuropathic pain
- patients undergoing
- liver failure
- escherichia coli
- anti inflammatory
- acute kidney injury
- emergency department
- risk assessment
- drug induced
- physical activity
- human health
- intensive care unit
- adverse drug
- young adults
- clinical decision support