Axial spondylarthritis following COVID-19 infection.
Rajesh GopalarathinamShainy NawimanaAlbert Selva-O'CallaghanPublished in: BMJ case reports (2023)
Although SARS-CoV-2 syndrome primarily affects the lungs, systemic manifestations have been reported. New rheumatic immune-mediated inflammatory diseases have been reported following SARS-CoV-2 infection. We present a case of a woman in her mid-30s who developed inflammatory back pain due to bilateral sacroiliitis with erosions after contracting SARS-CoV-2 infection. Her inflammatory markers on presentation were normal. MRI of the sacroiliac joints demonstrated bone marrow oedema and erosive changes in both sacroiliac joints. As the patient was intolerant to non-steroidal anti-inflammatory drugs, adalimumab 40 mg subcutaneous (SC) injection was administered, which improved her symptoms in 8 weeks. However, due to the drug's side effects, SC adalimumab was switched to intravenous infliximab. The patient is currently tolerating her intravenous infliximab well and has experienced significant improvement in her symptoms. We reviewed the current literature on the prevalence of axial spondyloarthropathy after SARS-CoV-2 infection.
Keyphrases
- case report
- anti inflammatory drugs
- respiratory syndrome coronavirus
- sars cov
- rheumatoid arthritis
- ulcerative colitis
- bone marrow
- high dose
- oxidative stress
- systematic review
- magnetic resonance imaging
- juvenile idiopathic arthritis
- sleep quality
- contrast enhanced
- risk factors
- emergency department
- hidradenitis suppurativa
- low dose
- computed tomography
- diffusion weighted imaging
- gestational age
- physical activity
- depressive symptoms
- magnetic resonance
- disease activity