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The effects of iron overload, insulin resistance and oxidative stress on metabolic disorders in patients with β- thalassemia major.

Soheila SetoodehMarjan KhorsandMohammad Ali Takhshid
Published in: Journal of diabetes and metabolic disorders (2020)
Oxidative stress and iron overload are predictors of serum glycemic and lipid dysregulation, suggesting possible beneficial effect of antioxidants and efficient iron chelating therapy in reducing the risk of metabolic disorders in β- thalassemia.
Keyphrases
  • oxidative stress
  • insulin resistance
  • iron deficiency
  • type diabetes
  • dna damage
  • sickle cell disease
  • metabolic syndrome
  • induced apoptosis
  • adipose tissue
  • high fat diet
  • stem cells
  • skeletal muscle
  • heat shock
  • bone marrow