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Rasal1 regulates calcium dependent neuronal maturation by modifying microtubule dynamics.

M H S DeurlooS EideE TurlovaQ LiS SpijkerH-S SunA J A GroffenZhong-Ping Feng
Published in: Cell & bioscience (2024)
Rasal1 functions in two separate roles in neuronal development; calcium regulated neurite outgrowth and the promotion of NMDA receptor-mediated postsynaptic events which may be mediated both by interaction with direct binding partners or calcium-dependent regulation of down-stream pathways. Importantly, the outlined molecular mechanisms of Rasal1 may contribute notably to normal neuronal development and synapse formation.
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