Epigenetic clocks indicate that kidney transplantation and not dialysis mitigate the effects of renal ageing.
Ognian NeytchevHelen ErlandssonAnna WitaspLouise NordforsAbdul Rashid QureshiKen IseriHokuto MorohoshiColin SelmanThomas EbertKarolina KublickieneStenvinkel PeterPaul G ShielsPublished in: Journal of internal medicine (2023)
Kidney failure patients displayed an increased biological age as estimated by DNAm clocks compared to population-based controls. Our results suggest that KT, but not dialysis, partially reduces the age acceleration.