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Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma.

Shu-Hong LinJoshua N SampsonThomas G P GrünewaldDidier SurdezStephanie ReynaudOlivier MirabeauEric KarlinsRebeca Alba RubioSakina ZaidiSandrine Grossetête-LalamiStelly BalletEve LapoubleValérie LaurenceJean MichonGaelle PierronHeinrich KovarUdo KontnyAnna González-NeiraJavier AlonsoAna Patino-GarciaNadège CorradiniPerrine Marec BérardJeremy MillerNeal D FreedmanNathaniel RothmanBrian D CarterCasey L DagnallLaurie BurdettKristine JonesMichelle ManningKathleen WyattWeiyin ZhouMeredith YeagerDavid G CoxRobert N HooverJaved KhanGregory T ArmstrongWendy M LeisenringSmita BhatiaLeslie L RobisonAndreas E KulozikJennifer KriebelThomas MeitingerMarkus MetzlerManuela KrumbholzWolfgang HartmannKonstantin StrauchThomas KirchnerUta DirksenLisa MirabelloMargaret A TuckerFranck TirodeLindsay M MortonStephen J ChanockOlivier DelattreMitchell J Machiela
Published in: PloS one (2020)
Motivate future targeted sequencing studies for a comprehensive evaluation of low-frequency and rare variation around common EwS susceptibility loci.
Keyphrases
  • genome wide
  • genome wide association study
  • genome wide association
  • single cell
  • current status
  • dna repair
  • cancer therapy
  • dna methylation
  • case control
  • gene expression
  • dna damage
  • oxidative stress