Immune profile of adipose tissue from youth with obesity and asthma.
Anna ReichenbachWade O'BrienSarai DuranKayla J AutheletRobert J FreishtatEvan P NadlerDeepa RastogiPublished in: Pediatric obesity (2023)
Enrichment of macrophage-mediated inflammation in VAT from youth with obesity-related asthma supports its role in systemic inflammation linked with asthma morbidity. Lack of correlation of VAT cells with metabolic dysregulation in youth with obesity-related asthma identifies a need to define distinguishing factors associated with VAT inflammation in obesity-related asthma.
Keyphrases
- insulin resistance
- chronic obstructive pulmonary disease
- lung function
- adipose tissue
- metabolic syndrome
- weight loss
- allergic rhinitis
- type diabetes
- high fat diet induced
- weight gain
- mental health
- oxidative stress
- physical activity
- young adults
- high fat diet
- induced apoptosis
- body mass index
- skeletal muscle
- air pollution
- gene expression
- cell proliferation
- pi k akt