Atrophy of the hippocampal CA1 subfield relates to long-term forgetting in focal epilepsy.

Takahiko Mukaino Taira UeharaJun YokohamaToshiki OkadomeTomomi ArakawaSetsu YokoyamaAyumi SakataKei-Ichiro TakaseOsamu TogaoNaoki AkamatsuHiroshi ShigetoNoriko IsobeJun-Ichi Kira

Published in: Epilepsia (2022)

Our results suggest that atrophy of the hippocampal CA1 region and its associated structures disrupts long-term memory consolidation in focal epilepsy. Neuronal cell loss in specific hippocampal subfields could be a key underlying cause of ALF in patients with epilepsy.

Keyphrases

temporal lobe epilepsy
cerebral ischemia
single cell
cell therapy
high resolution
blood brain barrier
stem cells
protein kinase
brain injury
mesenchymal stem cells
bone marrow