Genetic and psychosocial stressors have independent effects on the level of subclinical psychosis: findings from the multinational EU-GEI study.
Baptiste PignonH PeyreAnaël AyrollesJames Bowes KirkbrideS JamainA FerchiouJ R RichardG BaudinSarah TosatoH JongsmaL de HaanI TarriconeM BernardoE VelthorstM BracaC ArangoM ArrojoJ BobesC M Del-BenM Di FortiC Gayer-AndersonP B JonesC La CasciaAntonio LasalviaP R MenezesD QuattroneJ SanjuánJ P SeltenA TortelliP M LlorcaJ van OsB P F RuttenR M MurrayMorgan CraigM LeboyerA SzökeF SchürhoffPublished in: Epidemiology and psychiatric sciences (2022)
This study in subjects without psychotic disorders suggests that (i) the aetiological continuum hypothesis could concern particularly the positive dimension of subclinical psychosis, (ii) genetic and environmental factors have independent effects on the level of this positive dimension, (iii) and that interactions between genetic and individual environmental factors could not be identified in this sample.