Effect of diabetes medications and glycemic control on risk of hepatocellular cancer in patients with non-alcoholic fatty liver disease.
Jennifer R KramerYamini NatarajanJianliang DaiXian YuLiang LiHashem El-SeragFasiha KanwalPublished in: Hepatology (Baltimore, Md.) (2021)
In this large cohort of patients with NAFLD and DM, use of metformin was associated with a reduced risk of HCC while use of combination therapy was associated with increased risk. Glycemic control can serve as a biomarker for HCC risk stratification in patients with NAFLD and diabetes.