World Health Organization risk drinking levels as a treatment outcome measure in topiramate trials.
Emily E HartwellRichard FeinnKatie A WitkiewitzTimothy PondHenry R KranzlerPublished in: Alcoholism, clinical and experimental research (2021)
Topiramate is an efficacious pharmacotherapy for AUD. Although continuous measures of drinking and alcohol-related problems yielded larger effect sizes than the WHO RDLs, the latter nonetheless provide a categorical alternative for use in both clinical care and pharmacotherapy trials.