Characterization and microRNA Expression Analysis of Serum-Derived Extracellular Vesicles in Severe Liver Injury from Chronic HBV Infection.

Min LiuXionghao LiuMengmeng PanYu ZhangXiangling TangWanxi LiuMingri ZhaoJing MaNing ZhouYongfang JiangWenlong WangMujun Liu

Published in: Life (Basel, Switzerland) (2023)

The patients with severe liver injury-CHB had the highest number of EVs. The combination of novel-miR-172-5p and miR-1285-5p in serum EVs helped in predicting the progression of the NCs to severe liver injury-CHB, while the addition of EV miR-335-5p improved the serological accuracy of predicting the progression of severe liver injury-CHB to DeCi.

Keyphrases

liver injury
drug induced
early onset
hepatitis b virus
transcription factor