Does Gadolinium Deposition Lead to Metabolite Alteration in the Dentate Nucleus? An MRS Study in Patients with MS.

M Mohammadzadeh Shahriar Kolahi Mohammad-Mehdi Mehrabi Nejad Kavous Firouznia H Naghibi Ali Mohammadzadeh M Shakiba F Mohebi Hamidreza Komaki Hashem Sharifian H Hashemi M H Harirchian Amir Reza Azimi Mehmet Emin Adin David M Yousem

Published in: AJNR. American journal of neuroradiology (2022)

Although elevated concentrations of Cr, lactate, mIns, and lipid in the dentate nucleus of the case group indicate a metabolic disturbance, NAA and choline levels were normal, implying no definite neuronal damage.

Keyphrases

mass spectrometry
multiple sclerosis
oxidative stress
ms ms
blood brain barrier
subarachnoid hemorrhage