Alterations in pain processing circuitries in episodic migraine.
Tiffani J MungovenKasia K MarciszewskiVaughan G MacefieldPaul M MaceyLuke A HendersonNoemi MeylakhPublished in: The journal of headache and pain (2022)
These data reveal that the modulation of brainstem pain modulatory areas by higher cortical regions may be aberrant during pain and these alterations in this descending pain modulatory pathway manifests exclusively prior to the development of a migraine attack.