A Nanopore Sequencing-based Pharmacogenomic Panel to Personalize Tuberculosis Drug Dosing.

Renu VermaKesia Esther da SilvaNeesha RockwoodRoeland E WasmannNombuso YendeTaeksun SongEugene KimPaolo Denti Robert John WilkinsonJason R Andrews

Published in: American journal of respiratory and critical care medicine (2024)

Targeted sequencing can enable detection of polymorphisms influencing TB drug metabolism on a low-cost, portable instrument to personalize dosing for TB treatment or prevention. This article is open access and distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).

Keyphrases

low cost
mycobacterium tuberculosis
single cell
adverse drug
minimally invasive
pulmonary tuberculosis
cancer therapy
hiv aids
drug induced
emergency department
clinical decision support
combination therapy
replacement therapy
human immunodeficiency virus
quantum dots
antiretroviral therapy