Long-Term Observation of Cyclosporine as Second-Line Therapy in Adults for Severe Acute Autoimmune Hepatitis.

Fumie NoguchiPo-Sung ChuNobuhito TanikiAya YoshidaRei MorikawaAkihiro YamaguchiAkihiko IkuraKarin YamatakaHitomi HoshiShingo UsuiHirotoshi EbinumaHidetsugu SaitoTakanori KanaiNobuhiro Nakamoto

Published in: Hepatology (Baltimore, Md.) (2021)

Severe acute-onset autoimmune hepatitis (SA-AIH), a possible cause of acute liver failure (ALF), poses great challenges in diagnosis and management. Latest guidelines and expert reviews advocate a trial of corticosteroids (CS) followed by assessments of their clinical effect for 1-2 weeks with consideration for liver transplantation (LT).

Keyphrases

liver failure
hepatitis b virus
multiple sclerosis
clinical practice
drug induced
study protocol
phase iii
phase ii
extracorporeal membrane oxygenation