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Histone deacetylase Sir2 promotes the systemic Candida albicans infection by facilitating its immune escape via remodeling the cell wall and maintaining the metabolic activity.

Chen YangGuanglin LiQiyue ZhangWenhui BaiQingiqng LiPeipei ZhangJiye Zhang
Published in: mBio (2024)
pathogenicity in detail; these findings provide a potential target for the development of antifungal drugs.
Keyphrases
  • candida albicans
  • histone deacetylase
  • cell wall
  • biofilm formation
  • human health
  • drug induced
  • risk assessment
  • escherichia coli