PPAR-γ Agonist Alleviates Liver and Spleen Pathology via Inducing Treg Cells during Schistosoma japonicum Infection.

Yuxiao ZhuYangyue Ni Ran LiuMin HouBingya YangJingwei SongHongzhi SunZhi-Peng Xu Minjun Ji

Published in: Journal of immunology research (2018)

Our study reveals a previously unrecognized role for PPAR-γ/Foxp3 signaling in regulating the immunopathology that occurs during Schistosoma infection through induction of Treg cells.

Keyphrases

induced apoptosis
cell cycle arrest
regulatory t cells
signaling pathway
type diabetes
immune response
adipose tissue
pi k akt