Salidroside attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ 1-42 -induced Alzheimer's disease mice and glutamate-injured HT22 cells.
Sixia YangZeping XieTingting PeiYi ZengQiaowu XiongHui WeiYong WangWeidong ChengPublished in: Chinese medicine (2022)
-induced AD mice and Glu-injured HT22 cells, and its mechanism is related to activation of the Nrf2/HO1 signaling pathway.
Keyphrases
- signaling pathway
- induced apoptosis
- pi k akt
- cell cycle arrest
- oxidative stress
- diabetic rats
- high glucose
- endoplasmic reticulum stress
- epithelial mesenchymal transition
- cell death
- drug induced
- cell proliferation
- type diabetes
- cognitive decline
- adipose tissue
- endothelial cells
- skeletal muscle
- blood brain barrier
- stress induced