A population pharmacokinetic model is beneficial in quantifying hair concentrations of ritonavir-boosted atazanavir: a study of HIV-infected Zimbabwean adolescents.

Bernard NgaraSimbarashe ZvadaTariro Dianah ChawanaBabill Stray-PedersenCharles Fungai Brian NhachiSimbarashe Rusakaniko

Published in: BMC pharmacology & toxicology (2020)

The determinants of increased ATV/r concentrations in hair found in our analysis are monitoring at follow up event, body mass index, and caregiver status. Measuring drug concentration in hair is feasibly accomplished and could be more accurate for monitoring ARV drugs exposure.

Keyphrases

hiv infected
antiretroviral therapy
young adults
hiv infected patients
physical activity
high resolution
emergency department
drug induced
hepatitis c virus