The armadillo-repeat containing X-linked protein 3, ARMCX3, is a negative regulator of the browning of adipose tissue associated with obesity.

Aleix Gavaldà-Navarro Serena MirraYasmina MansoDavid Sánchez-InfantesMarta GiraltEduardo SorianoFrancesc Villarroya

Published in: International journal of obesity (2005) (2022)

ARMCX3 is a novel player in the control of thermogenic adipose tissue plasticity that acts to repress acquisition of the browning phenotype and shows a direct association with indicators of obesity in mice and humans.

Keyphrases

high fat diet induced
insulin resistance
adipose tissue
high fat diet
metabolic syndrome
skeletal muscle
weight loss
transcription factor
physical activity
weight gain
protein protein
binding protein
body mass index