Clinical characteristics associated with COVID-19 severity in California.
Samuel J S RubinSamuel R FalksonNicholas R DegnerCatherine BlishPublished in: Journal of clinical and translational science (2020)
Given the rapidly progressing coronavirus disease 2019 (COVID-19) pandemic, this report on a US cohort of 54 COVID-19 patients from Stanford Hospital and data regarding risk factors for severe disease obtained at initial clinical presentation is highly important and immediately clinically relevant. We identified low presenting oxygen saturation as predictive of severe disease outcomes, such as diagnosis of pneumonia, acute respiratory distress syndrome, and admission to the intensive care unit, and also replicated data from China suggesting an association between hypertension and disease severity. Clinicians will benefit by tools to rapidly risk stratify patients at presentation by likelihood of progression to severe disease.
Keyphrases
- coronavirus disease
- acute respiratory distress syndrome
- sars cov
- early onset
- blood pressure
- electronic health record
- emergency department
- big data
- healthcare
- mechanical ventilation
- type diabetes
- palliative care
- metabolic syndrome
- intensive care unit
- respiratory syndrome coronavirus
- machine learning
- deep learning
- respiratory failure
- artificial intelligence
- glycemic control
- weight loss