Novel anti-cytoplasmic antibodies in cerebrospinal fluid and serum of patients with chronic severe mental disorders.
Dominique EndresBenjamin PankratzSarah ThiemKimon RungeAndrea SchlumpBernd FeigeKathrin NickelMarco ReisertHansjörg MastHorst UrbachMiriam A SchieleKatharina DomschkeBenjamin BergerNils VenhoffHarald PrüssLudger Tebartz van ElstPublished in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2022)
The detection of autoantibodies in CSF of chronic SMD may be beneficial in selecting some patients for immunotherapy. The possible impact of novel anti-cytoplasmic antibodies in this context is critically discussed. Further research is needed to establish the underlying pathophysiological processes as well as their diagnostic and therapeutic implications.