MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer.
Si Min ZhengYu Chen FengQin ZhuRuo Qi LiQian Qian YanLiu TengYi Meng YueMan Man HanKaihong YeSheng Nan ZhangTeng Fei QiCai Xia TangXiao Hong ZhaoYuan Yuan ZhangLiang XuRan XuJun XingMark Andrew BakerTao LiuRick Francis ThorneLei JinThomas PreissYuan Yuan ZhangShundong CangJin Nan GaoPublished in: Cancer research (2024)
LncRNA MILIP plays a key role in supporting protein production in TNBC by forming complexes with tRNAs and eEF1α1, which confers sensitivity to combined MILIP targeting and protein synthesis inhibitors.