EpiPanGI Dx: A Cell-free DNA Methylation Fingerprint for the Early Detection of Gastrointestinal Cancers.

Raju Kandimalla Jianfeng Xu Alexander LinkTakatoshi MatsuyamaKensuke YamamuraMohamed Iqbal ParkerHiroyuki UetakeFrancesc BalaguerErkut Hasan BorazanciSusan TsaiDouglas B EvansStephen J MeltzerHideo BabaRandall E Brand Daniel D Von HoffWei LiAjay Goel

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)

Using a novel biomarker discovery approach, we provide the first evidence for a cfDNA methylation assay that offers robust diagnostic accuracy for GI cancers.

Keyphrases

cell free
dna methylation
genome wide
high throughput
small molecule
gene expression
circulating tumor
young adults
circulating tumor cells